Trudy Triumph's Neurogenic Bladder Blog

Potential of Stem Cell Therapy for the Neurogenic Bladder

The time is ripe, I hear. within our lifetimes. There is hope for more than just treatment, but an actual cure . . . the flood gates are open through life-saving research that is happening as I type….
What are Stem Cells?

 
Adult Stem cells are cells with high proliferative and self-renewal capacities derived from adults. They can come from many areas of the body including bone marrow, Breast milk, dental pulp and fat; the safest to use of course are your own.
Fat derived stem cells cells: Can be used to repress disease responding cells such as those involved in multiple sclerosis and other auto immune diseases.

 
Bone Marrow Stem cells: Can help with some Cancers, Heart Failure, and other vascular diseases, as well as diabetes.

Human Umbilical Cord Tissue: Can help those who suffer from inflammation and central nervous system issues. Because these cells are less mature the host body is less able to recognize them as being brought into a host vs. graft situation. They are also considered more “potent”.

Embryonic Stem Cells:
Cells derived from the BLASTOCYST INNER CELL MASS which forms before implantation in the uterine wall. They retain the ability to divide, proliferate and provide progenitor cells that can differentiate into specialized cells.

Fetal Stem Cells:
Cells derived from a FETUS that retain the ability to divide, proliferate and provide progenitor cells that can differentiate into specialized cells.

Ok what exactly is the goal of stem cell therapy for spinal injuries?

1. Generating new supporting cells that will re-form the insulating nerve sheath (myelin) and act as a bridge across the injury to stimulate re-growth of damaged axons

2. Protecting the cells at the injury site from further damage by releasing protective substances such as growth factors, and soaking up toxins such as free radicals, when introduced into the spinal cord shortly after injury and preventing spread of the injury by suppressing the damaging inflammation that can occur after injury.

Link Euro Stem Cell

Review Article: Non-traditional management of the neurogenic bladder: tissue engineering and neuromodulation.

There are many stem cell sources that are non-controversial, yet the one type that gets the most press could indeed help an injured person but at what cost?

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